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HHMI BioInteractive brings the power of real science stories into tens of thousands of high school and undergraduate life science classrooms. Their stories anchor a variety of classroom resources based on peer-reviewed science. From data-rich activities and case studies to high-quality videos and interactive media, their resources are designed to connect students to big ideas in biology, promote engagement with science practices, and instill awe and wonder about the living world. In addition, the BioInteractive website provides educators with planning tools to build resource playlists and storylines, and professional learning materials, and opportunities to deepen their scientific and pedagogical expertise. Their resources and tools reflect current knowledge of how students learn and evidence-based strategies for supporting engagement and inclusion. They also believe inspiration, curiosity, and love of the natural world should be nurtured outside of the classroom, and they partner with filmmakers to bring high-quality science films to everyone.